phyx

所属分类:其他
开发工具:C++
文件大小:24490KB
下载次数:0
上传日期:2023-02-09 15:54:17
上 传 者sh-1993
说明:  linux(和其他主要兼容posix的)计算机的系统发生学工具
(phylogenetics tools for linux (and other mostly posix compliant) computers)

文件列表:
LICENSE (35148, 2023-07-24)
deps (0, 2023-07-24)
deps\Optional (0, 2023-07-24)
deps\Optional\atlas3.10.2.tar.bz2 (4904923, 2023-07-24)
deps\Optional\lapack-3.4.2.tgz (6168281, 2023-07-24)
deps\armadillo-7.400.2.tgz (5806640, 2023-07-24)
deps\gmpfrxx (0, 2023-07-24)
deps\gmpfrxx\COPYING (35147, 2023-07-24)
deps\gmpfrxx\Makefile (848, 2023-07-24)
deps\gmpfrxx\example.cpp (3579, 2023-07-24)
deps\gmpfrxx\gmp-4.3.1.tar.bz2 (1881090, 2023-07-24)
deps\gmpfrxx\gmpfrxx.cpp (3841, 2023-07-24)
deps\gmpfrxx\gmpfrxx.h (166186, 2023-07-24)
deps\gmpfrxx\libgmpfrxx.a (81946, 2023-07-24)
deps\gmpfrxx\mpfr-2.4.2.tar.gz (1412116, 2023-07-24)
deps\gmpfrxx\mpfr_mul_d.c (1386, 2023-07-24)
deps\gmpfrxx\mpfr_mul_d.h (589, 2023-07-24)
deps\nlopt-2.4.2.tar.gz (2361992, 2023-07-24)
doc (0, 2023-07-24)
doc\Phyxed_Manual.aux (4078, 2023-07-24)
doc\Phyxed_Manual.out (146, 2023-07-24)
doc\Phyxed_Manual.pdf (114860, 2023-07-24)
doc\Phyxed_Manual.tex (22531, 2023-07-24)
doc\Programs.md (18886, 2023-07-24)
example_files (0, 2023-07-24)
example_files\manuscript_example (0, 2023-07-24)
example_files\manuscript_example\test.fa (18072, 2023-07-24)
example_files\manuscript_example\test0.fa (18072, 2023-07-24)
example_files\manuscript_example\test1.fa (18072, 2023-07-24)
example_files\manuscript_example\test2.fa (18072, 2023-07-24)
example_files\manuscript_example\test3.fa (18072, 2023-07-24)
example_files\manuscript_example\test4.fa (18072, 2023-07-24)
... ...

[![Build-N-Test](https://github.com/FePhyFoFum/phyx/actions/workflows/build-test.yml/badge.svg)](https://github.com/FePhyFoFum/phyx/actions/workflows/build-test.yml) phyx logo --- **_Note_** Phyx recently overwent an overhaul such that a simple `git pull && git make` will fail. Instead, see instructions [here](#problems-after-updating-git-pull). --- **phyx** performs phylogenetics analyses on trees and sequences. See installation instructions for Linux and Mac including any dependencies on the wiki [here](https://github.com/FePhyFoFum/phyx/wiki/Installation) or below. Authors: Joseph W. Brown\*, Joseph F. Walker\*, and Stephen A. Smith (\* equal contribution) Citation: [Brown, J. W., J. F. Walker, and S. A. Smith; Phyx: phylogenetic tools for unix. Bioinformatics 2017; 33 (12): 1886-1888. doi: 10.1093/bioinformatics/btx063](https://academic.oup.com/bioinformatics/article/33/12/1886/2975328/Phyx-phylogenetic-tools-for-unix) License: GPL https://www.gnu.org/licenses/gpl-3.0.html Some of the sequence comparison operations use the very nice [edlib library](https://github.com/Martinsos/edlib#alignment-methods). These are reported in this publication: [Martin Sosic, Mile Sikic; Edlib: a C/C ++ library for fast, exact sequence alignment using edit distance. Bioinformatics 2017 btw753. doi: 10.1093/bioinformatics/btw753](https://academic.oup.com/bioinformatics/article/33/9/1394/29***763/Edlib-a-C-C-library-for-fast-exact-sequence). ## Documentation Documentation resides in several locations (all slightly out of date, alas). A [pdf manual](https://github.com/FePhyFoFum/phyx/tree/master/doc) is available in the `doc/` directory. A slightly-less-out-of-date list of the current programs with examples can be found [on the wiki](https://github.com/FePhyFoFum/phyx/wiki/Program-list). Help for individual programs can be obtained with either `PROGRAM -h` or (if installed, see below) `man PROGRAM`. See a brief overview [here](https://twitter.com/i/moments/10678395***927008769). Still, there are a whack of programs, so it can be difficult to remember the name of which program does what. Here is a quick reference: Program | Short description :--- | :--- pxaa2cdn | produce a codon alignment from and AA alignment and unaligned nucleotides pxbdfit | diversification model inference pxbdsim | a birth death simulator pxboot | sequence alignment resampling (bootstrap or jackknife) pxbp | prints out bipartitions that make up the tree pxcat | an alignment concatenator pxclsq | clean sites based on missing or ambiguous data pxcltr | general tree cleaner pxcolt | collapse poorly-supported edges pxcomp | a composition homogeneity test pxcomp | compositional homogeneity test pxconsq | a consensus sequence constructor for an alignment pxcontrates | a brownian and ou estimator pxfqfilt | a fastq filter given a mean quality pxlog | a MCMC log manipulator/concatenator pxlssq | information about seqs in a file (like ls but for an alignment file) pxlstr | information about trees in a file (like ls but for a tree file) pxmono | monophyly tester pxmrca | information about an mrca pxmrcacut | a mrca cutter pxmrcaname | a mrca label maker pxnj | neighbour-joining tree inference pxnni | a nni changer pxnw | needleman-wunsch alignment pxpoly | a polytomy sampler that generates a binary tree pxrecode | a sequence alignment recoder pxrevcomp | a reverse complementor pxrls | taxon relabelling for sequences pxrlt | taxon relabelling for trees pxrmk | remove two-degree nodes from a tree pxrms | pruning seqs (like rm but for seqs) pxrmt | pruning trees (like rm but for trees) pxrr | rerooting and unrooting trees pxs2fa | convert an alignment to fasta format pxs2nex | convert an alignment to nexus format pxs2phy | convert an alignment to phylip format pxseqgen | sequence simulation program pxssort | sequence sorter pxssplit | split alignment into N individual sequence files pxsstat | multinomial alignment test statistics pxstrec | a state reconstructor pxsw | smith waterman alignment pxt2new | convert a tree to newick format pxt2nex | convert a tree to vanilla Nexus format pxtcol | annotate tree to colour edges pxtcomb | tree combiner pxtgen | exhaustive tree topology generator pxtlate | translate nucleotide sequences into amino acids pxtrt | extract an induced subtree from a larger tree pxtscale | tree rescaling pxupgma | upgma tree inference pxvcf2fa | convert vcf file to fasta alignment ## Problems after updating (git pull) If you have been using phyx and things are not working after a recent pull, this is because of a change in configuration. Please do the following in the `src` directory to remedy the situation: make distclean autoreconf -fi ./configure make make check sudo make install # Installation instructions phyx requires a few dependencies. Since installation of these dependencies differs on [Linux](#linux-install) vs. [Mac OSX](#mac-install), we've separated the instructions below. ## Mac install Mac has become increasingly difficult to support at the command line with changes every version on location and standards for compilation tools. First, distribution of compiled programs is very difficult. Furthermore, Mac now defaults to clang as a C/C++ compiler, which does not support OpenMP. For **Mac OSX 10.12**, we have found that you can install with clang using the simple instructions and [homebrew](http://brew.sh/) *or* using a fresh installation of gcc from [here](http://hpc.sourceforge.net/). Instructions for both are below (don't use both, choose one, probably the simple one). For simple instructions click [here](#binary-install-with-homebrew), and for advanced instructions click [here](#install-with-hpc-gcc-advanced-instructions). ### Binary install with Homebrew 1. Install the Homebrew package manager: /usr/bin/ruby -e "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/master/install)" 2. Install the Brewsci phyx package: brew install brewsci/bio/phyx ### Build from source with Homebrew 1. Install the Homebrew package manager: /usr/bin/ruby -e "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/master/install)" 2. Install dependencies from homebrew: brew install git cmake nlopt armadillo 3. On to phyx. First, clone the repository (if you haven't already): git clone https://github.com/FePhyFoFum/phyx.git 4. Install phyx cd phyx/src autoconf ./configure make make check If you want to install it so it is available anywhere in your system, do: sudo make install ### Install with HPC GCC (advanced instructions) 1. Install gcc and gfortran. Download gcc-6.2-bin.tar.gz or more recent from http://hpc.sourceforge.net/. Install with: sudo tar -xvf gcc-6.2-bin.tar -C / 2. Install autoconf from http://ftp.gnu.org/gnu/autoconf/. Get autoconf-latest.tar.gz, then: tar -xzf autoconf-latest.tar.gz cd autoconf-2.69 ./configure --prefix=/usr/local/autoconf-2.69 make sudo make install ln -s autoconf-2.69 /usr/local/autoconf 3. On to phyx. first, clone the repository (if you haven't already): git clone https://github.com/FePhyFoFum/phyx.git 4. Install cmake and install Armadillo. Get cmake from https://cmake.org/download/. I got https://cmake.org/files/v3.6/cmake-3.6.2-Darwin-x86_***.tar.gz. Get armadillo from the `deps` directory or http://arma.sourceforge.net/download.html, get the stable one. Untar it. Double click the Cmake.app. Click "Browse source..." and choose the armadillo folder that was created after untaring. Click "Browse build..." and choose the same folder as browse source. Click "Configure" and then click "Generate". Go to the terminal and browse to that armadillo folder and type: make sudo make install 5. Install nlopt. Get armadillo from the `deps` directory or go to http://ab-initio.mit.edu/wiki/index.php/NLopt#Download_and_installation and download the latest (probably nlopt-2.4.2.tar.gz). Untar and browse in the terminal to that directory: ./configure --without-octave --without-matlab make sudo make install 6. Compile phyx. Now you can go to the src directory of phyx and type: autoconf ./configure make make check sudo make install and all the programs should compile without issue. ## Linux install These instructions work for most ubuntu versions as well as debian. 1. Install general dependencies: sudo apt-get install git autotools-dev autoconf automake cmake libtool liblapack-dev libatlas-cpp-0.6-dev libnlopt-cxx-dev 2. Clone the phyx repo (if you haven't already): git clone https://github.com/FePhyFoFum/phyx.git 3. Install armadillo dependency **Note**: it is possible to get from apt-get, but need version >= 5.2: sudo apt-get install libarmadillo-dev On debian it was necessary to use backports: sudo apt-get -t jessie-backports install libarmadillo-dev If that is not possible, compile the provided code: cd phyx/deps tar -xvzf armadillo-7.400.2.tgz cd armadillo-7.400.2 ./configure make sudo make install 4. Finally, install phyx: cd phyx/src autoconf ./configure make make check If you want to install it so it is available anywhere in your system, do: sudo make install

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