CFP

所属分类:生物医药技术
开发工具:Python
文件大小:0KB
下载次数:0
上传日期:2023-05-23 12:10:39
上 传 者sh-1993
说明:  蛋白质组学中心代码。,
(Code for the Center for Proteomics.,)

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snp_fasta.py (2862, 2023-05-23)

## How to use the snp_fasta.py This script adds entries to an existing fasta. All missense SNPs from the mutations.csv file are searched and a number of AA before and after the SNP are added. 1. Get the mutations file Look for your cell line of interest on [DepMap](https://depmap.org/portal/) and download the mutations.csv file. 2. Install needed packages: ```bash pip install SeqIO ``` 3. Run the python script: For example, run the code with the following arguments: - fasta file: test.fasta - mutations file: mutations.csv - number of AAs before and after the mutation: 15 - output fasta: MUT_test.fasta ```bash python --fasta_file test.fasta --snp_file mutations.csv --num_aa 15 --output_file MUT_test.fasta ```

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