genetic-associations-visualization

所属分类:人工智能/神经网络/深度学习
开发工具:HTML
文件大小:0KB
下载次数:0
上传日期:2023-12-05 15:34:10
上 传 者sh-1993
说明:  生命科学编程项目
(A project in programming in the life sciences)

文件列表:
AUTHORS (15, 2023-12-05)
CONTRIBUTING.md (1196, 2023-12-05)
LICENSE (1064, 2023-12-05)
Source Code/ (0, 2023-12-05)
Source Code/Source Code.html (9600, 2023-12-05)
images/ (0, 2023-12-05)
images/Demonstration.png (141972, 2023-12-05)
images/Image (1, 2023-12-05)
images/Wikidata Entry.png (199278, 2023-12-05)

# Description It is known that certain diseases have genetic predispositions. However, we also know that genetic predispositions are often not only related to one disease, but perhaps also with other diseases. This tool allows the user to investigate whether a certain disease has any genetic predispositions in common with other diseases, such as autoimmune diseases. The data is fetched from the Wikidata SPARQL endpoint. The SPARQL query used in the project is located in the script section of the [source code](https://github.com/Abi2222/Programming-in-the-Life-Sciences-PRA3006-/blob/main/Source%20Code/Source%20Code.html). # Question Are any of the genetic predispositions for certain disease also present in other diseases? # Screenshots Website ![](https://github.com/Abi2222/Programming-in-the-Life-Sciences-PRA3006-/blob/main/images/Demonstration.png) A Wikidata entry for Inflammatory Bowel Diseases ![](https://github.com/Abi2222/Programming-in-the-Life-Sciences-PRA3006-/blob/main/images/Wikidata%20Entry.png) # Usage * Download the source code [source code](https://github.com/Abi2222/Programming-in-the-Life-Sciences-PRA3006-/blob/main/Source%20Code/Source%20Code.html) by clicking the download button above the code * Open the file in a web browser. You will see Inflammatory Bowel Diseases' genetic common genetic predispositions which is the default * Explore the interactive pie chart to understand the shared genetic predispositions * Hover over the segments to view more detailed information about genes and associated diseases * Use the search functionality to find the case for other diseases. Note that you need to find the Wikidata entry for the disease and write the ID (Q...) into the search box. Example below ![Hello](https://github.com/Abi2222/Programming-in-the-Life-Sciences-PRA3006-/blob/main/images/Wikidata%20Entry.png) # Dependencies The code utilizes D3.js functions to create, update, and handle interactions with the pie chart, as well as to manipulate the DOM (Document Object Model) for dynamic visualizations. # Areas for Improvement If you wish to contribute, please see the instructions [here](https://github.com/Abi2222/Programming-in-the-Life-Sciences-PRA3006-/blob/main/CONTRIBUTING.md). Here are some identified issues: * The user needs to manually search the Wikidata entry to find the Wikidata ID for a disease, it might be possible to skip this step

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